Mixers SYMEX CML500

process engineering / machines and plants for process engineering / Mixers

The Symex CML 500 is a high-performance vacuum homogenizing mixer for the production of demanding products in the pharmaceutical and cosmetic industries. The system combines mixing, dispersing, homogenizing, heating, cooling and vacuum processing in a closed system, enabling precise and ...

Manufacturer: SYMEX

Model:CML500

Type of machine: Mixers

item-No.: 169409233

Quantity: 1

Date: 28.04.2026

Year of manufacture:

Location: Land-de Germany

Price:


Machine in stock:Yes

The Symex CML 500 is a high-performance vacuum homogenizing mixer for the production of demanding products in the pharmaceutical and cosmetic industries.

The system combines mixing, dispersing, homogenizing, heating, cooling and vacuum processing in a closed system, enabling precise and reproducible production – from pilot scale to industrial application.
Such systems are specially designed for complex processes with high quality requirements.

Technical Highlights of the Symex CML 500

Containers
- Usable volume: approx. 500 litres
- Total volume: approx. 780 litres
- Minimum volume: approx. 125–160 litres
- Pressure range product space: -1 / +2 bar
-Product temperature: up to approx. 133 °C
-Heating jacket: up to +4 bar / 151 °C
-AD 2000 design
-The container is designed to be completely pressure- and vacuum-resistant and enables safe processes under demanding conditions.

Agitator
- Armature agitator with current breakers
- Speed range: approx. 11–66 rpm
- Power: approx. 7.5 kW
- Frequency-controlled
- Designed for high-viscosity products
- The agitator ensures uniform mixing and optimal heat transfer.

Homogenizer
- Power: approx. 16–20 kW
- Speed: up to approx. 3,000 rpm
- High shear performance for fine dispersion
- Rotor/stator system
- The homogenizer ensures stable emulsions and reproducible product qualities.

Vacuum system
- Operation under vacuum possible
- Liquid ring vacuum pump (external)
- Pressure and vacuum monitoring
- Vacuum operation reduces air ingress and significantly improves product quality.

Heating & Cooling
- Double-walled container (2-zone heating)
- Precise temperature control
- Uniform heat distribution
- CIP system

Multiple CIP ports
- Rotating cleaning nozzles (360°)
- Cleaning of the entire product area including pipes

Raw material intake
- Direct suction of liquids and powders
- Suction into the homogenizer area
- Fast and low-loss processing
- Such integrated feed and circulation systems enable very efficient process control.

Other equipment
- Hydraulic lid lifting device
- Multi-bell with multiple connection options
- Sight glass with double wiper
- Lighting in the container
- Dosing container (approx. 8 litres)
- Sampling valve
- Diaphragm and Butterfly Valves
- Circulating pipes for homogenization and CIP
- Control & Operation

The system has a modern operating concept:
- Touch panel control
- Setting of speeds and running times
- Process monitoring (pressure, temperature, speed)
- Automatic and manual operating modes
- Fault messages and safety functions
- Advantages of the Symex CML 500

Combination of all process steps in one system
- High process reliability due to closed design
- Reproducible and stable product quality
- Suitable for highly viscous and sensitive products
- Hygienic design (GMP compatible)
- Flexible application options for different batch sizes

Delivery & Handling
- Delivery of Ex-Works
- Turn-key project possible (incl. commissioning)
- International shipping available
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The Symex CML 500 is a high-performance vacuum homogenizing mixer for the production of demanding products in the pharmaceutical and cosmetic industries.

The system combines mixing, dispersing, homogenizing, heating, cooling and vacuum processing in a closed system, enabling precise and reproducible production – from pilot scale to industrial application.
Such systems are specially designed for complex processes with high quality requirements.

Technical Highlights of the Symex CML 500

Containers
- Usable volume: approx. 500 litres
- Total volume: approx. 780 litres
- Minimum volume: approx. 125–160 litres
- Pressure range product space: -1 / +2 bar
-Product temperature: up to approx. 133 °C
-Heating jacket: up to +4 bar / 151 °C
-AD 2000 design
-The container is designed to be completely pressure- and vacuum-resistant and enables safe processes under demanding conditions.

Agitator
- Armature agitator with current breakers
- Speed range: approx. 11–66 rpm
- Power: approx. 7.5 kW
- Frequency-controlled
- Designed for high-viscosity products
- The agitator ensures uniform mixing and optimal heat transfer.

Homogenizer
- Power: approx. 16–20 kW
- Speed: up to approx. 3,000 rpm
- High shear performance for fine dispersion
- Rotor/stator system
- The homogenizer ensures stable emulsions and reproducible product qualities.

Vacuum system
- Operation under vacuum possible
- Liquid ring vacuum pump (external)
- Pressure and vacuum monitoring
- Vacuum operation reduces air ingress and significantly improves product quality.

Heating & Cooling
- Double-walled container (2-zone heating)
- Precise temperature control
- Uniform heat distribution
- CIP system

Multiple CIP ports
- Rotating cleaning nozzles (360°)
- Cleaning of the entire product area including pipes

Raw material intake
- Direct suction of liquids and powders
- Suction into the homogenizer area
- Fast and low-loss processing
- Such integrated feed and circulation systems enable very efficient process control.

Other equipment
- Hydraulic lid lifting device
- Multi-bell with multiple connection options
- Sight glass with double wiper
- Lighting in the container
- Dosing container (approx. 8 litres)
- Sampling valve
- Diaphragm and Butterfly Valves
- Circulating pipes for homogenization and CIP
- Control & Operation

The system has a modern operating concept:
- Touch panel control
- Setting of speeds and running times
- Process monitoring (pressure, temperature, speed)
- Automatic and manual operating modes
- Fault messages and safety functions
- Advantages of the Symex CML 500

Combination of all process steps in one system
- High process reliability due to closed design
- Reproducible and stable product quality
- Suitable for highly viscous and sensitive products
- Hygienic design (GMP compatible)
- Flexible application options for different batch sizes

Delivery & Handling
- Delivery of Ex-Works
- Turn-key project possible (incl. commissioning)
- International shipping available
seller offer No. resale 169409233
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SEEFRIED Verfahrenstechnik GmbH

Mr Andre Seefried
28844 Weyhe
Germany

RESALE member since 2017

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